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Scientist/Senior Scientist, Cell Type Development

BitBio

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Posted over 30 days ago...

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Join BitBio as they are looking for a Scientist/Senior Scientist, Cell Type Development

Overview

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No salary declared 😔

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Cambridge, UK

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Expires at anytime

bit.bio is an award-winning spinout from the University of Cambridge. Our breakthrough technology combines synthetic and stem cell biology for the precise, efficient and consistent reprogramming of human cells used in research, drug discovery, and cell therapy. At bit.bio, we are passionate about engineering human cells that will enable the medicine of the future. To do this we need talented and curious people who want to make an impact on the future of science and therapeutics.

As a team of individuals, we value science, collaboration, openness, curiosity and creativity. We are united by trust and respect for each other.

Location: Babraham Research Park, Cambridge

Type: Full time, permanent 

Start: Immediate

Salary: Competitive / Hours: 40 p/w

Lab based position

Your role in our team:

We are looking for a Scientist / Senior Scientist with a strong background in stem cells, cellular differentiation, cellular reprogramming/forward programming, and/or cell characterisation, to support our efforts in and the generation of a variety of cell types from pluripotent stem cells. This post is focused on, but not limited to, the derivation of cells types from endoderm and mesoderm derived-tissues. Thus, we encourage applications from all backgrounds within the cellular differentiation and reprogramming fields.

As a Scientist / Senior Scientist within Cell Type Development, you will become the specialist of a specific cell type within the team. This will be achieved based on your previous knowledge and experience, or through actively generating the background knowledge required to become so. Reporting to the Team Leader along with the Director of Cell Type Development, the candidate will work with a team of researchers as a focal point within the wider R&D department for the generation of new cell types from pluripotent stem cells.

Your key responsibilities will include:

  • Driving the development and execution of experiments to generate cell types of interest from human pluripotent stem cells, using cellular reprogramming approaches.
  • Analysis and interpretation of data from cellular reprogramming experiments, reporting of data, and experimental troubleshooting as required.
  • Coordinating cross-functional efforts within bit.bio, and beyond, to characterise the cell types of interest generated through the Cell Type Development process.
  • Supporting the design, development, and implementation of the Cell Type Development team. This includes assay design/implementation/execution, LIMS/samples tracking, resource management, SOP writing and process development.
  • Contributing towards the completion of documentation and reports required during the Cell Type Development process and its milestone stage-gates.
  • Facilitating technology transfer across teams within bit.bio.
  • In collaboration with the Team Leader, support the cell line development and delivery of experimental data and project updates to a wide variety of stakeholders.

You…

  • Have a MSc/PhD in a relevant area of Biological Sciences (or equivalent experience) with proven experience in academia and/or industry and a passion for problem solving. 
  • Have a strong background in developing and/or characterising cell-based models from different sources.
  • Have a background and experience in stem cell biology / cellular differentiation / cellular reprogramming.
  • Are a good team player with an inquisitive mind and an ability to prioritise, organise, and be responsible for your own workload and that of others.
  • Thrive in an environment with challenging scientific questions and enjoy researching novel approaches to tackle problems.
  • Will be looking for a stimulating working environment where you can engage with different working groups to independently drive research projects and actively contribute to projects of others.

With essential experience in... 

  • Strong practical and theoretical background in hESC or hiPSC culture and/or differentiation/reprogramming approaches and/or functional cell type expertise - experiment planning, execution, and critical interpretation of generated data, and project delivery.
  • Well-rounded practical experience in molecular assays, molecular biology, and their downstream analysis (qRT-PCR, ELISA, ICC, Flow, bulk and/or single cell RNA sequencing).
  • The ability to manage and prioritise own workload.
  • The ability to work collaboratively between teams and specific platforms.
  • Working and performing in a highly collaborative environment.

and possibly...

  • Experience with working with endoderm and/or mesoderm derived cell types.
  • Experience and understanding of introducing novel workflows/processes and the development of screens for cellular differentiation.
  • Experience with training people and leading multiple projects.

More reasons to join us:

bit.bio provides a vibrant and dynamic work environment in an exciting, fast-moving time for biology. We work with cutting edge technologies and with our world-leading scientific advisory board. We conduct pioneering work with real-world impact.

We trust our people to make significant contributions early on with opportunities to be involved in projects that are key to the success and growth of our young company. We invest in people, creating opportunities for personal development in an inclusive multi-skilled team with ambitious goals that provide opportunities to learn on the job from each other.

Creativity and open minds are encouraged for everyone to contribute to the success of the company.

For information on how we will manage your data please see our Candidate Privacy Notice

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